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The old antipsychotic drugs are just as dangerous as the new ones when given to elderly patients with Dementia. In this study of 890 patients over the age of 65, 18% of those given a conventional drug were dead, compared with 15% of those given an the new drugs after 180 days. New England Journal Medicine
Payment to Doctors for patient recruitment to clinical trials has not been studied well despite millions of dollars paid to physicians who conduct such trials by the pharmaceutical companies. Knowing that pharmaceutical companies do not usually spend money unless they know they will get something in return, and physician bias that can occur when they are paid thousands of dollars per each patients, more studies are needed to make sure these trials are conducted well and that these influences would not affect the outcome. Etanica Medical Review
Marijuana use appears to increase the risk of fatal car crash in a study of 10 748 drivers, with known drug and alcohol concentrations, who were involved in fatal crashes in France from October 2001 to September 2003. This increased risk was independent of alcohol although alcohol certainly has a greater risk. British Medical Journal
Morphine,
Neurontin, and Their Combination for
Neuropathic Pain
In
a randomized trial, the combination of
morphine and gabapentin
led
to better pain control than either
agent alone in patients
with
diabetic neuropathy or postherpetic
neuralgia. The dose
of each
agent was lower when used in
combination than when used
alone.
Adverse effects were not more severe
with the combined
formulation.
These
findings suggest that treatment with
the combined formulation
of
morphine and gabapentin for
neuropathic pain is superior
to
treatment with either agent alone.
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