Obstetrics and Gynecologic Problems

Hepatitis C testing for antibody to hepatitis C may not be enough to screen organ donors. Unfortunately a recent report in the Annals of Internal Medicine showed transmission of hepatitis C to organ donor recipients from an organ donor whose hepatitis C antibody testing was actually negative. Later testing for Hepatitis C Nucleic Acid testing was positive in this organ donor. Since an organ donor tissues such as tendons, skin,  cornea can be given to as many as 100 recipients, a more through screening of the donors may have to be done.

Bacterial infection of vagina, is a serious health problem for millions of women. This condition is not very well understood. This New England Journal of Medicine study showed that these infections are complicated and involve number of different bacterias some of which were rather specific for this problem and of Clostridiales family. This hopefully should result in finding a more effective treatment for these patients.

Presece of certain genes in Lupus patients can be associated with risk factors such as stoke and heart attack as was reported in the New England Journal of Medicine. Mannose-binding lectin gene are associated with Lupus as well as with severe atherosclerosis. In this study, author showed that those patients with Lupus who have homozygosity for this gene are at increased risk of developing arterial blockage such as stroke and heart attack.

D-Dimer blood test that is done to look for possible blood clots is most accurate when done by enzyme-linked immunosorbent assays (ELISAs) that had the highest sensitivity and lowest negative likelihood ratio, which makes ELISA the best D-dimer test for excluding blood clots in legs and lungs.

Fosomax is effective in preventing bone loss and reduced the rates of fracture after cardiac transplantation. The New England Journal of Medicine

New osteoporosis drug, strontium ranelate, an orally active drug that dissociates bone remodeling by increasing bone formation and decreasing bone resorption. This study showed that strontium ranelate was able to reduce the risk of  vertebral fractures and to increase bone mineral density. The New England Journal Of Medicine

 
 

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