Topical NSAIDs such as those made with anti-inflammatory medications such as Volteran of Ketoprofen (similar to aspirin and motrin) were no better than placebo in patients with Osteoarthritis as reported in the British Medical Journal (BMJ).

For patients with proliferative lupus nephritis, short-term treatment with intravenous Cytoxan followed by maintenance therapy with mycophenolate mofetil or azathioprine appears to be more effective and safer than long-term therapy with intravenous Cytoxan. The New England Journal of Medicine