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Hepatitis C
testing for
antibody to hepatitis C may not be enough to screen organ donors. Unfortunately a recent report in the Annals of Internal Medicine showed transmission of hepatitis C to organ donor recipients from an organ donor whose hepatitis C antibody testing was actually negative. Later testing for
Hepatitis C Nucleic Acid testing was positive in this organ donor. Since an organ donor tissues such as tendons, skin, cornea can be given to as many as 100 recipients, a more through screening of the donors may have to be done.
Treatment
of selected patients with AL amyloidosis,
a fatal disease resulting from
tissue
deposition of amyloid fibrils derived
from monoclonal
immunoglobulin
light chains,
by
using high-dose melphalan and
stem-cell transplantation resulted
in hematologic remission,
improved 5-year survival from 5 months
to 4.8 years, and reversal
of
amyloid-related disease in a
substantial proportion (40%).
This study showed that there are
better treatments now available for
Amyloidosis with increase in rates of
remission and survival.
The
Annals of Internal Medicine
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