Liver, Intestines, and other Abdominal Problems

Hepatitis C testing for antibody to hepatitis C may not be enough to screen organ donors. Unfortunately a recent report in the Annals of Internal Medicine showed transmission of hepatitis C to organ donor recipients from an organ donor whose hepatitis C antibody testing was actually negative. Later testing for Hepatitis C Nucleic Acid testing was positive in this organ donor. Since an organ donor tissues such as tendons, skin,  cornea can be given to as many as 100 recipients, a more through screening of the donors may have to be done.

Treatment of selected patients with AL amyloidosis, a fatal disease resulting from tissue deposition of amyloid fibrils derived from monoclonal immunoglobulin light chains,  by using high-dose melphalan and stem-cell transplantation resulted in hematologic remission, improved 5-year survival from 5 months to 4.8 years, and reversal of amyloid-related disease in a substantial proportion (40%). This study showed that there are better treatments now available for Amyloidosis with increase in rates of remission and survival. The Annals of Internal Medicine

 
 

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  Medical Editor